Rabbit polyclonal rprd1b antibody (A10102)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal rprd1b antibody (A10102)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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C20orf77 antibody|Chromosome 20 open reading frame 77 antibody|CREPT antibody|dJ1057B20.2 antibody|DKFZp434P0735 antibody|FLJ44520 antibody|Hypothetical protein LOC58490 antibody|NET60 antibody|Regulation of nuclear pre mRNA domain containing 1B antibody|Regulation of nuclear pre mRNA domain containing protein 1B antibody|Uncharacterized protein C20orf77 antibody|Anti-C20orf77 antibody (ab154910)

SCBT cat No:

Name

Rabbit polyclonal rprd1b antibody

Catalogue No.

A10102

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human rprd1b

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 37kDa/Observed: Refer to figures

Formulation

rprd1b antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

rprd1b antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q9NQG5

Protein function

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3′ end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.

Protein tissue specificity

Preferentially expressed in a range of tumor tissues including colon, lung, liver, breast, prostate, stomach, uterine endometrium and cervical cancers with higher levels in tumors than in adjacent non-tumor tissue (at protein level).

Protein sequence and domain

Belongs to the UPF0400 (RTT103) family.; Contains 1 CID domain.

Protein cellular localization

Nucleus .

Note

AntibodyPlus can customize rprd1b antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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