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Rabbit polyclonal rprd1b antibody (A10102)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal rprd1b antibody.
Check alternative names for the antibodyExpand
C20orf77 antibody|Chromosome 20 open reading frame 77 antibody|CREPT antibody|dJ1057B20.2 antibody|DKFZp434P0735 antibody|FLJ44520 antibody|Hypothetical protein LOC58490 antibody|NET60 antibody|Regulation of nuclear pre mRNA domain containing 1B antibody|Regulation of nuclear pre mRNA domain containing protein 1B antibody|Uncharacterized protein C20orf77 antibody|Anti-C20orf77 antibody (ab154910)
SCBT cat No:
Rabbit polyclonal rprd1b antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human rprd1b
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 37kDa/Observed: Refer to figures
rprd1b antibody was tube-contained.
rprd1b antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3′ end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
|Protein tissue specificity|| |
Preferentially expressed in a range of tumor tissues including colon, lung, liver, breast, prostate, stomach, uterine endometrium and cervical cancers with higher levels in tumors than in adjacent non-tumor tissue (at protein level).
|Protein sequence and domain|| |
Belongs to the UPF0400 (RTT103) family.; Contains 1 CID domain.
|Protein cellular localization|| |
AntibodyPlus can customize rprd1b antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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