Rabbit polyclonal RRM1 antibody (A1152)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal RRM1 antibody (A1152)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal RRM1 antibody.

Alternative names:

Check alternative names for the antibody

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RRM1 antibody,R1 antibody,RIR1 antibody,RR1 antibody
R1 antibody|Ribonucleoside diphosphate reductase large subunit antibody|Ribonucleoside diphosphate reductase M1 chain antibody|Ribonucleoside diphosphate reductase subunit M1 antibody|Ribonucleoside reductase, large subunit antibody|Ribonucleoside-diphosphate reductase large subunit antibody|Ribonucleoside-diphosphate reductase subunit M1 antibody|Ribonucleotide reductase large chain antibody|Ribonucleotide reductase large subunit antibody|Ribonucleotide reductase M1 antibody|Ribonucleotide reductase M1 polypeptide antibody|Ribonucleotide reductase R1 subunit antibody|Ribonucleotide reductase, M1 subunit antibody|RIR 1 antibody|RIR1 antibody|RIR1_HUMAN antibody|RR 1 antibody|RR1 antibody|RRM 1 antibody|RRM1 antibody|Anti-RRM1 antibody [EPR8483] (ab137114)

SCBT cat No: sc-377415|sc-377426|sc-22786|sc-11733|

Name

Rabbit polyclonal RRM1 antibody

Catalogue No.

A1152

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human RRM1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 90kDa/Observed: Refer to Figures

Formulation

RRM1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

RRM1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

RRM1 antibody,R1 antibody,RIR1 antibody,RR1 antibody

Database links

Human UniProt/Swiss-Prot:P23921

Protein names

RRM1,R1,RIR1,RR1

Protein function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

Protein sequence and domain

Belongs to the ribonucleoside diphosphate reductase large chain family.; Contains 1 ATP-cone domain.

Protein cellular localization

Cytoplasm.

Background

Ribonucleotide reductase catalyzes the rate-limiting step in the synthesis of deoxynucleotide triphosphates (dNTPs). The regulatory M1 subunit (RRM1) is present throughout the cell division cycle, but downregulated in quiescent cells (1). Research studies have demonstrated that RRM1 is involved in carcinogenesis and tumor progression, and its expression is correlated with resistance to chemotherapy in non-small cell lung cancer (2-4).

Note

AntibodyPlus can customize RRM1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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