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Rabbit polyclonal RRM2 antibody (A5255)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal RRM2 antibody.
Check alternative names for the antibodyExpand
R2 antibody,RR2M antibody
cb111 antibody|chunp6884 antibody|etID309896.20 antibody|R2 antibody|reductase M2 polypeptide variant 1 antibody|reductase M2 polypeptide variant 2 antibody|reductase M2 polypeptide variant 3a antibody|reductase M2 polypeptide variant 3b antibody|reductase M2 polypeptide variant 3c antibody|reductase M2 polypeptide variant 3d antibody|Ribonucleoside-diphosphate reductase subunit M2 antibody|Ribonucleotide reductase M2 antibody|Ribonucleotide reductase M2 polypeptide antibody|Ribonucleotide reductase M2 subunit antibody|ribonucleotide reductase protein r2 class I antibody|Ribonucleotide reductase regulatory subunit M2 antibody|Ribonucleotide reductase small chain antibody|Ribonucleotide reductase small subunit antibody|Ribonucleotide reductase, R2 subunit antibody|RIR2_HUMAN antibody|RR2 antibody|RR2M antibody|RRM2 antibody|Anti-RRM2 antibody (ab57653)
SCBT cat No: sc-398294|sc-10846|sc-10848|sc-10844|sc-81850|
Rabbit polyclonal RRM2 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human RRM2
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 45kDa/Observed: Refer to Figures
RRM2 antibody was tube-contained.
RRM2 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
R2 antibody,RR2M antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
|Protein sequence and domain|| |
Belongs to the ribonucleoside diphosphate reductase small chain family.
|Protein post-translational modifications|| |
Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
|Protein cellular localization|| |
Ribonucleotide reductase M2 subunit is one of two subunits that constitute ribonucleotide reductase, the enzyme that catalyzes the conversion of ribonucleotide 5′-diphosphates into 2′-deoxyribonucleotides, a rate-limiting step in the production of 2′-deoxyribonucleoside 5′-diphosphates (dNTP) required for DNA synthesis and repair that is required for DNA synthesis and repair [PMID:20825972, 19250552]. RRM2 is only expressed during the late G1/early S phase, and degraded in late S phase, and the activity of RNR, and therefore DNA synthesis and cell proliferation, is controlled during the cell cycle by the synthesis and degradation of RRM2 subunit.
AntibodyPlus can customize RRM2 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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