Rabbit polyclonal RUFY1 antibody (A7836)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal RUFY1 antibody (A7836)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal RUFY1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

RABIP4 antibody, ZFYVE12 antibody
3000002E04Rik antibody|FLJ22251 antibody|FYVE finger protein EIP1 antibody|FYVE-finger protein EIP1 antibody|La binding protein 1 antibody|La-binding protein 1 antibody|OTTHUMP00000161521 antibody|Rab4 interacting protein antibody|Rab4-interacting protein antibody|RABIP4 antibody|RUFY1 antibody|RUFY1_HUMAN antibody|RUN and FYVE domain containing 1 antibody|RUN and FYVE domain-containing protein 1 antibody|RUN and FYVE domains containing protein 1 antibody|ZFYVE12 antibody|Zinc finger FYVE domain containing protein 12 antibody|Zinc finger FYVE domain-containing protein 12 antibody|Anti-RUFY1 antibody (ab155217)

SCBT cat No: sc-398740|sc-100846|

Name

Rabbit polyclonal RUFY1 antibody

Catalogue No.

A7836

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human RUFY1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 80kDa/Observed: Refer to figures

Formulation

RUFY1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

RUFY1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

RABIP4 antibody, ZFYVE12 antibody

Database links

Human UniProt/Swiss-Prot:Q96T51

Protein names

RABIP4, ZFYVE12

Protein function

Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.

Protein tissue specificity

Broadly expressed, with highest levels in lung, testis, kidney and brain.

Protein sequence and domain

The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate in membranes of early endosomes and penetrates bilayers. The FYVE domain insertion into PtdIns(3)P-enriched membranes is substantially increased in acidic conditions.Contains 1 FYVE-type zinc finger.; Contains 1 RUN domain.

Protein post-translational modifications

Phosphorylation on Tyr-389 and/or Tyr-400 is required for interaction with BMX and endosomal targeting.

Protein cellular localization

Cytoplasm. Early endosome membrane; Peripheral membrane protein.

Background

This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Note

AntibodyPlus can customize RUFY1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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