Rabbit polyclonal SCYL1 antibody (A6735)

A6735

Recombinant protein of human SCYL1

WB, IHC, IF

Polyclonal

IgG

SCYL1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Human UniProt/Swiss-Prot:Q96KG9

Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum . Involved in the maintenance of the Golgi apparatus morphology . Has no detectable kinase activity in vitro .; Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region.

The protein kinase domain is predicted to be catalytically inactive.Belongs to the protein kinase superfamily.; Contains 3 HEAT repeats.; Contains 1 protein kinase domain.

This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.

AntibodyPlus can customize SCYL1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

ABclonal Inc.