Rabbit polyclonal SCYL1 antibody (A6735)

$69.00$259.00

Reactivity: Human,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal SCYL1 antibody (A6735)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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GKLP antibody, NKTL antibody, NTKL antibody, P105 antibody, TAPK antibody, TEIF antibody, TRAP antibody, HT019 antibody
Coated vesicle associated kinase of 90 kDa antibody|Coated vesicle-associated kinase of 90 kDa antibody|CVAK90 antibody|GKLP antibody|HT019 antibody|Likely ortholog of mouse N terminal kinase like protein antibody|MGC78454 antibody|N terminal kinase like antibody|N terminal kinase like protein antibody|N-terminal kinase-like protein antibody|NKTL antibody|NTKL antibody|NTKL_HUMAN antibody|NTKLBP1 antibody|P105 antibody|SCY L1 antibody|SCY1 like 1 antibody|SCY1 like 1 protein 1 antibody|SCY1-like protein 1 antibody|SCYL 1 antibody|Scyl1 antibody|SCYL1BP1 antibody|TAPK antibody|TEIF antibody|Telomerase regulation associated protein antibody|Telomerase regulation-associated protein antibody|Telomerase transcriptional element interacting factor antibody|Telomerase transcriptional element-interacting factor antibody|Teratoma associated tyrosine kinase antibody|Teratoma-associated tyrosine kinase antibody|TRAP antibody|Anti-SCYL1 antibody (ab76851)

SCBT cat No:

Name

Rabbit polyclonal SCYL1 antibody

Catalogue No.

A6735

Reactivity

Human, Rat

Immunogen

Recombinant protein of human SCYL1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 89kDa/Observed: Refer to Figures

Formulation

SCYL1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

SCYL1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GKLP antibody, NKTL antibody, NTKL antibody, P105 antibody, TAPK antibody, TEIF antibody, TRAP antibody, HT019 antibody

Database links

Human UniProt/Swiss-Prot:Q96KG9

Protein names

GKLP, NKTL, NTKL, P105, TAPK, TEIF, TRAP, HT019

Protein function

Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum . Involved in the maintenance of the Golgi apparatus morphology . Has no detectable kinase activity in vitro .; Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region.

Protein tissue specificity

Ubiquitous.

Protein sequence and domain

The protein kinase domain is predicted to be catalytically inactive.Belongs to the protein kinase superfamily.; Contains 3 HEAT repeats.; Contains 1 protein kinase domain.

Protein cellular localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Endoplasmic reticulum-Golgi intermediate compartment . Golgi apparatus, cis-Golgi network . Note: Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1-independent manner.; Isoform 1: Cytoplasm. Note: Cytoplasmic throughout the cell cycle.; Isoform 2: Cytoplasm. Note: Cytoplasmic throughout the cell cycle.; Isoform 3: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note: Cytoplasmic during interphase and centrosomal during mitosis, it localizes to the centrosomes in a microtubule-independent manner.; Isoform 6: Nucleus .

Background

This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Research area

All research areas>Additional Gene Products>SCYL
(View all antibody categories related to Additional Gene Products)

Note

AntibodyPlus can customize SCYL1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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