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Rabbit polyclonal SECISBP2 antibody (A6736)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
DKFZp686C09169 antibody|OTTHUMP00000064929 antibody|OTTHUMP00000064930 antibody|OTTHUMP00000064931 antibody|OTTHUMP00000064932 antibody|RP11 89K14.1 antibody|SBP 2 antibody|SBP2 antibody|SEBP2_HUMAN antibody|SECIS binding protein 2 antibody|SECIS-binding protein 2 antibody|SECISBP 2 antibody|SECISBP2 antibody|Selenocysteine insertion sequence binding protein 2 antibody|Selenocysteine insertion sequence-binding protein 2 antibody|Anti-SECISBP2 antibody (ab53534)
SCBT cat No:
Rabbit polyclonal SECISBP2 antibody
|Catalogue No.|| |
Recombinant protein of human SECISBP2
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 95kDa/Observed: Refer to figures
SECISBP2 antibody was tube-contained.
SECISBP2 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Binds to the SECIS element in the 3′-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
|Protein tissue specificity|| |
Expressed at high levels in testis.
|Protein cellular localization|| |
Isoform 1: Nucleus .; Isoform 2: Mitochondrion .
The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
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|Product type|| |
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