Rabbit Polyclonal SEPT9 antibody (A8657)

$99.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal SEPT9 antibody (A8657)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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MSF antibody; MSF1 antibody; NAPB antibody; SINT1 antibody; PNUTL4 antibody; SeptD1 antibody; AF17q25
AF17q25 antibody|Cell division control protein septin D1 antibody|KIAA0991 antibody|MLL septin like fusion protein antibody|MLL septin-like fusion protein antibody|MLL septin-like fusion protein MSF-A antibody|MSF antibody|MSF1 antibody|NAPB antibody|Ov/Br septin antibody|Ovarian/breast septin alpha antibody|Ovarian/Breast septin antibody|PNUTL4 antibody|SEPT9 antibody|SEPT9_HUMAN antibody|SeptD1 antibody|Septin 9 antibody|Septin D1 antibody|Septin-9 antibody|SINT1 antibody|Anti-MSF antibody (ab38314)

SCBT cat No:

Name

Rabbit Polyclonal SEPT9 antibody

Catalogue No.

A8657

Reactivity

Human

Immunogen

Recombinant protein of human SEPT9

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

65kDa

Formulation

SEPT9 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MSF antibody; MSF1 antibody; NAPB antibody; SINT1 antibody; PNUTL4 antibody; SeptD1 antibody; AF17q25

Protein names

MSF; MSF1; NAPB; SINT1; PNUTL4; SeptD1; AF17q25

Protein function

Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Protein tissue specificity

Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues.

Protein sequence and domain

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.; Contains 1 septin-type G (guanine nucleotide-binding) domain.

Protein cellular localization

Cytoplasm, cytoskeleton . Note=In an epithelial cell line, concentrates at cell-cell contact areas. After TGF-beta1 treatment and induction of epithelial to mesenchymal transition, colocalizes partly with actin stress fibers. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria.

Background

This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Note

AntibodyPlus can customize SEPT9 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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