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Rabbit Polyclonal SIGLEC8 antibody (A10514)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit Polyclonal SIGLEC8 antibody.
Check alternative names for the antibodyExpand
CD329 antigen antibody|CDw329 antibody|SAF 2 antibody|SAF-2 antibody|SAF2 antibody|Sialic acid binding Ig like lectin 8 antibody|Sialic acid-binding Ig-like lectin 8 antibody|Sialoadhesin family member 2 antibody|SIGL8_HUMAN antibody|Siglec 8 antibody|Siglec-8 antibody|SIGLEC8 antibody|SIGLEC8L antibody|Anti-SIGLEC8 antibody (ab38578)
SCBT cat No:
Rabbit Polyclonal SIGLEC8 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human SIGLEC8
|Recommended dilution|| |
WB 1:500 – 1:2000
SIGLEC8 antibody was tube-contained.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/Q9NYZ4">Q9NYZ4</a>
|Protein function|| |
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
|Protein tissue specificity|| |
Expressed specifically on eosinophils.
|Protein sequence and domain|| |
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.; Contains 2 Ig-like C2-type (immunoglobulin-like) domains.; Contains 1 Ig-like V-type (immunoglobulin-like) domain. Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Lymphocyte-Signaling/">Lymphocyte Signaling</a>><a href="http://antibodyplus.com/product-tag/Siglec-7/">Siglec-7</a><br><a href="http://antibodyplus.com/product-tag/Lymphocyte-Signaling/"> (View all antibody categories related to Lymphocyte Signaling)</a>
AntibodyPlus can customize SIGLEC8 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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