Rabbit Polyclonal SIGLEC8 antibody (A10514)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal SIGLEC8 antibody (A10514)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

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CD329 antigen antibody|CDw329 antibody|SAF 2 antibody|SAF-2 antibody|SAF2 antibody|Sialic acid binding Ig like lectin 8 antibody|Sialic acid-binding Ig-like lectin 8 antibody|Sialoadhesin family member 2 antibody|SIGL8_HUMAN antibody|Siglec 8 antibody|Siglec-8 antibody|SIGLEC8 antibody|SIGLEC8L antibody|Anti-SIGLEC8 antibody (ab38578)

SCBT cat No:

Name

Rabbit Polyclonal SIGLEC8 antibody

Catalogue No.

A10514

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human SIGLEC8

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

SIGLEC8 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Protein function

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Protein tissue specificity

Expressed specifically on eosinophils.

Protein sequence and domain

Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.; Contains 2 Ig-like C2-type (immunoglobulin-like) domains.; Contains 1 Ig-like V-type (immunoglobulin-like) domain. Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Lymphocyte-Signaling/">Lymphocyte Signaling</a>><a href="http://antibodyplus.com/product-tag/Siglec-7/">Siglec-7</a><br><a href="http://antibodyplus.com/product-tag/Lymphocyte-Signaling/"&gt; (View all antibody categories related to Lymphocyte Signaling)</a>

Note

AntibodyPlus can customize SIGLEC8 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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