Rabbit Polyclonal SLC22A4 antibody (A10490)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal SLC22A4 antibody (A10490)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:1000 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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OCTN1 antibody;
Ergothioneine transporter antibody|ET transporter antibody|integral membrane transport protein antibody|LSTP Like 2 antibody|MGC34546 antibody|MGC40524 antibody|Octn1 antibody|Organic cation transporter 1 antibody|Organic cation/carnitine transporter 1 antibody|RP23-354D12.1 antibody|S22A4_HUMAN antibody|Slc22a4 antibody|Solute carrier family (organic cation transporter), member 4 antibody|solute carrier family 22 (organic cation/zwitterion transporter), member 4 antibody|Solute carrier family 22 member 4 antibody|Anti-SLC22A4 antibody (ab200641)

SCBT cat No: sc-33534|

Name

Rabbit Polyclonal SLC22A4 antibody

Catalogue No.

A10490

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human SLC22A4

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

62kDa

Formulation

SLC22A4 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

OCTN1 antibody;

Protein names

OCTN1;

Protein function

Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78. A key substrate of this transporter seems to be ergothioneine (ET).

Protein tissue specificity

Widely expressed. Highly expressed in whole blood, bone marrow, trachea and fetal liver. Weakly expressed in kidney, skeletal muscle, prostate, lung, pancreas, placenta, heart, uterus, spleen and spinal cord. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells. Predominantly expressed in CD14 cells in peripheral blood mononuclear cells.

Protein sequence and domain

Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

Protein cellular localization

Membrane; Multi-pass membrane protein.

Background

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent.

Note

AntibodyPlus can customize SLC22A4 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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