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Rabbit Polyclonal SLC22A4 antibody (A10490)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:1000 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit Polyclonal SLC22A4 antibody.
Check alternative names for the antibodyExpand
Ergothioneine transporter antibody|ET transporter antibody|integral membrane transport protein antibody|LSTP Like 2 antibody|MGC34546 antibody|MGC40524 antibody|Octn1 antibody|Organic cation transporter 1 antibody|Organic cation/carnitine transporter 1 antibody|RP23-354D12.1 antibody|S22A4_HUMAN antibody|Slc22a4 antibody|Solute carrier family (organic cation transporter), member 4 antibody|solute carrier family 22 (organic cation/zwitterion transporter), member 4 antibody|Solute carrier family 22 member 4 antibody|Anti-SLC22A4 antibody (ab200641)
SCBT cat No: sc-33534|
Rabbit Polyclonal SLC22A4 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human SLC22A4
|Recommended dilution|| |
WB 1:1000 – 1:2000
|Molecular weight|| |
SLC22A4 antibody was tube-contained.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/Q9H015">Q9H015</a>
|Protein names|| |
|Protein function|| |
Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78. A key substrate of this transporter seems to be ergothioneine (ET).
|Protein tissue specificity|| |
Widely expressed. Highly expressed in whole blood, bone marrow, trachea and fetal liver. Weakly expressed in kidney, skeletal muscle, prostate, lung, pancreas, placenta, heart, uterus, spleen and spinal cord. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells. Predominantly expressed in CD14 cells in peripheral blood mononuclear cells.
|Protein sequence and domain|| |
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
|Protein cellular localization|| |
Membrane; Multi-pass membrane protein.
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent.
AntibodyPlus can customize SLC22A4 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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