Rabbit Polyclonal SLC29A3 antibody (A10377)

$99.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal SLC29A3 antibody (A10377)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

ENT3 antibody; HJCD antibody; PHID antibody; HCLAP antibody;
ENT3 antibody|Equilibrative nucleoside transporter 3 antibody|HCLAP antibody|hENT3 antibody|HJCD antibody|PHID antibody|S29A3_HUMAN antibody|SLC29A3 antibody|Solute carrier family 29 (equilibrative nucleoside transporter) member 3 antibody|Solute carrier family 29 (nucleoside transporters) member 3 antibody|Solute carrier family 29 member 3 antibody|Rabbit Polyclonal to SLC29A3 (ab211421)

SCBT cat No: sc-48149|sc-48150|

Name

Rabbit Polyclonal SLC29A3 antibody

Catalogue No.

A10377

Reactivity

Human

Immunogen

Recombinant protein of human SLC29A3

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

52kDa

Formulation

SLC29A3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ENT3 antibody; HJCD antibody; PHID antibody; HCLAP antibody;

Protein names

ENT3; HJCD; PHID; HCLAP;

Protein function

Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine, as well as several nucleoside analog drugs, such as anticancer and antiviral agents, including cladribine, cordycepin, tubercidin and AZT. Does not transport hypoxanthine.

Protein tissue specificity

Widely expressed in both adult and fetal tissues. Highest levels in placenta, uterus, ovary, spleen, lymph node and bone marrow. Lowest levels in brain and heart.

Protein sequence and domain

Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.

Protein cellular localization

Membrane; Multi-pass membrane protein. Late endosome membrane. Lysosome membrane. Note=Observed in a punctate intracellular pattern showing partial colocalization with late endosomes/lysosomes. Not detected at the cell surface.

Background

This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.

Note

AntibodyPlus can customize SLC29A3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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