Rabbit Polyclonal SLC4A5 antibody (A10436)

$99.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal SLC4A5 antibody (A10436)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

NBC4 antibody; NBCe2 antibody;
Electrogenic sodium bicarbonate cotransporter 4 antibody|MGC129662 antibody|NBC4 antibody|NBCe2 antibody|S4A5_HUMAN antibody|SLC4A5 antibody|Solute carrier family 4 member 5 antibody|Solute carrier family 4 sodium bicarbonate cotransporter member 5 antibody|Anti-SLC4A5 antibody (ab99131)

SCBT cat No: sc-168713|sc-168715|

Name

Rabbit Polyclonal SLC4A5 antibody

Catalogue No.

A10436

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human SLC4A5

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

125kDa

Formulation

SLC4A5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NBC4 antibody; NBCe2 antibody;

Protein names

NBC4; NBCe2;

Protein function

Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry of 2:1. May have a housekeeping function in regulating the pH of tissues in which it is expressed. May play a role in mediating Na(+):HCO3(-) cotransport in hepatocytes and intrahepatic cholangiocytes. Also may be important in protecting the renal paranchyma from alterations in urine pH.

Protein tissue specificity

Highest expression observed in liver, spleen and testis; moderate expression in the choroid plexus, hippocampus, cerebrum and cerebellum of brain, and in kidney cortex and kidney medulla. Also observed in heart, pancreas, muscle, lung, placenta, stomach and small intestine. Weakest expression seen in peripheral blood lymphocytes, colon, duodenum, jejunum, ileum and skeletal muscle.

Protein sequence and domain

Belongs to the anion exchanger (TC 2.A.31) family.

Protein cellular localization

Apical cell membrane ; Multi-pass membrane protein . Note=Expressed in the apical plasma membrane domain of a subset of collecting ducts in the renal medulla.

Background

This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural or electrogenic sodium bicarbonate transport. This protein is thought to be an integral membrane protein. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Note

AntibodyPlus can customize SLC4A5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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