Rabbit Polyclonal SLC4A7 antibody (A10271)

$99.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal SLC4A7 antibody (A10271)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

NBC2 antibody; NBC3 antibody; SBC2 antibody; NBCN1 antibody; SLC4A6 antibody;
Bicarbonate transporter antibody|BT antibody|NBC2 antibody|NBC3 antibody|S4A7 antibody|SBC2 antibody|SLC4A6 antibody|Sodium bicarbonate cotransporter 2 antibody|Sodium bicarbonate cotransporter 2b antibody|Sodium bicarbonate cotransporter 3 antibody|Solute carrier family 4 member 7 antibody|Solute carrier family 4 sodium bicarbonate cotransporter member 7 antibody|Anti-SLC4A7 antibody (ab82335)

SCBT cat No:

Name

Rabbit Polyclonal SLC4A7 antibody

Catalogue No.

A10271

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human SLC4A7

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

136kDa

Formulation

SLC4A7 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NBC2 antibody; NBC3 antibody; SBC2 antibody; NBCN1 antibody; SLC4A6 antibody;

Protein names

NBC2; NBC3; SBC2; NBCN1; SLC4A6;

Protein function

Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity.

Protein tissue specificity

Highly expressed in testis and spleen. Also expressed in retina, colon, small intestine, ovary, thymus, prostate, muscle, heart and kidney. Isoform 1 is expressed in skeletal muscle and heart muscle.

Protein sequence and domain

Belongs to the anion exchanger (TC 2.A.31) family. The PDZ-binding motif mediates interaction with the CFTR, SLC9A3R1/EBP50 complex and probably with USH1C.

Protein cellular localization

Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane ; Multi-pass membrane protein . Cell projection, stereocilium . Note=Also described at the apical cell membrane. Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells (By similarity).

Background

This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Note

AntibodyPlus can customize SLC4A7 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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