Rabbit Polyclonal SNAPIN antibody (A10294)


Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal SNAPIN antibody (A10294)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:200 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


BLOS7 antibody; BORCS3 antibody; SNAPAP antibody; BLOC1S7 antibody;
OTTHUMP00000035157 antibody|SNAP associated protein antibody|SNAP-25-binding protein antibody|SNAP-associated protein antibody|SNAP25BP antibody|SNAPAP antibody|Snapin antibody|SNAPN_HUMAN antibody|SNARE associated protein snapin antibody|SNARE-associated protein Snapin antibody|Synaptosomal associated protein 25 binding protein antibody|Synaptosomal-associated protein 25-binding protein antibody|Anti-SNAPIN antibody (ab118392)

SCBT cat No:


Rabbit Polyclonal SNAPIN antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human SNAPIN











Molecular weight



SNAPIN antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


Affinity purification


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

BLOS7 antibody; BORCS3 antibody; SNAPAP antibody; BLOC1S7 antibody;

Protein names


Protein function

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells (PubMed:17182842, PubMed:18167355). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167).

Protein tissue specificity

Expressed in male germ cells of adult testis (at protein level).

Protein sequence and domain

Belongs to the SNAPIN family.

Protein post-translational modifications

Phosphorylated by CSNK1D/CK1 (By similarity). Phosphorylated by PKD, phosphorylation controls SNAPIN protein stability.

Protein cellular localization

Membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytosol . Cytoplasm, perinuclear region . Golgi apparatus membrane . Lysosome membrane . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Note=Colocalizes with NANOS1 and PUM2 in the perinuclear region of germ cells.


The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.


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Product type

Primary antibody


ABclonal Inc.


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