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Rabbit Polyclonal SNCB antibody (A10443)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit Polyclonal SNCB antibody.
Check alternative names for the antibodyExpand
14 kDa brain-specific protein antibody|Beta-synuclein antibody|Phosphoneuroprotein 14 antibody|PNP14 antibody|Sncb antibody|Synuclein beta antibody|SYUB_HUMAN antibody|Anti-beta Synuclein antibody [EP1537Y] (ab76111)
SCBT cat No: sc-136452|sc-9565|sc-9564|
Rabbit Polyclonal SNCB antibody
|Catalogue No.|| |
Recombinant protein of human SNCB
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
SNCB antibody was tube-contained.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/Q16143">Q16143</a>
|Protein function|| |
Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
|Protein tissue specificity|| |
Expressed predominantly in brain; concentrated in presynaptic nerve terminals.
|Protein sequence and domain|| |
Belongs to the synuclein family.
|Protein post-translational modifications|| |
Phosphorylated. Phosphorylation by G-protein coupled receptor kinases (GRK) is more efficient than phosphorylation by CK1, CK2 and CaM-kinase II.
|Protein cellular localization|| |
This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants.
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Neurobiology/">Neurobiology</a>><a href="http://antibodyplus.com/product-tag/synuclein/">synuclein</a><br><a href="http://antibodyplus.com/product-tag/Neurobiology/"> (View all antibody categories related to Neurobiology)</a>
AntibodyPlus can customize SNCB antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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