Rabbit Polyclonal SNX18 antibody (A10337)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal SNX18 antibody (A10337)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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SNAG1 antibody; SH3PX2 antibody; SH3PXD3B antibody;
FLJ11997 antibody|FLJ32560 antibody|FLJ61062 antibody|MGC150827 antibody|MGC150829 antibody|SH3 and PX domain containing protein 3B antibody|SH3 and PX domain-containing protein 3B antibody|SH3PX2 antibody|SH3PXD3B antibody|SNAG 1 antibody|SNAG1 antibody|SNX18 antibody|SNX18_HUMAN antibody|Sorting nexin 18 antibody|Sorting nexin associated golgi protein 1 antibody|Sorting nexin-18 antibody|Sorting nexin-associated Golgi protein 1 antibody|Anti-SNX18 antibody (ab111702)

SCBT cat No:

Name

Rabbit Polyclonal SNX18 antibody

Catalogue No.

A10337

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human SNX18

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

69kDa

Formulation

SNX18 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SNAG1 antibody; SH3PX2 antibody; SH3PXD3B antibody;

Protein names

SNAG1; SH3PX2; SH3PXD3B;

Protein function

Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.

Protein sequence and domain

Belongs to the sorting nexin family.; Contains 1 BAR domain.; Contains 1 PX (phox homology) domain.; Contains 1 SH3 domain. The PX domain mediates interaction with membranes enriched in phosphatidylinositol 4,5-bisphosphate.

Protein cellular localization

Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation.

Background

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize SNX18 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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