Rabbit Polyclonal TYMS antibody (A10441)

$99.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal TYMS antibody (A10441)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit Polyclonal TYMS antibody.

Alternative names:

Check alternative names for the antibody

Expand

TS antibody; TMS antibody; HST422 antibody;
d TMP synthase antibody|EC 2.1.1.45 antibody|HsT422 antibody|MGC88736 antibody|OTTHUMP00000162195 antibody|Thymidylate synthase antibody|Thymidylate synthetase antibody|TMS antibody|TS antibody|TSase antibody|Tyms antibody|TYMS protein antibody|Tyms thymidylate synthetase antibody|TYSY_HUMAN antibody|Anti-Thymidylate Synthase antibody [EPR4545] (ab108995)

SCBT cat No:

Name

Rabbit Polyclonal TYMS antibody

Catalogue No.

A10441

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human TYMS

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

34kDa

Formulation

TYMS antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

TS antibody; TMS antibody; HST422 antibody;

Protein names

TS; TMS; HST422;

Protein function

Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.

Protein sequence and domain

Belongs to the thymidylate synthase family.

Protein cellular localization

Nucleus . Cytoplasm . Mitochondrion . Mitochondrion matrix . Mitochondrion inner membrane .

Background

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.

Note

AntibodyPlus can customize TYMS antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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