Rabbit Polyclonal ULK2 antibody (STJ98597)


Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal ULK2 antibody (STJ98597)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody


ULK2 antibody, KIAA0623 antibody,|ATG1B antibody|KIAA0623 antibody|Serine/threonine protein kinase ULK2 antibody|Serine/threonine-protein kinase ULK2 antibody|ULK2 antibody|ULK2_HUMAN antibody|Unc 51 (C. elegans) like kinase 2 antibody|Unc 51 like autophagy activating kinase 2 antibody|Unc 51 like kinase 2 antibody|Unc-51-like kinase 2 antibody|Unc51.2 antibody|Anti-ULK2 antibody (ab97695)
SCBT cat No: To be updated



ULK2 Polyclonal Antibody

Catalogue No.



Human, Mouse, Rat


ULK2 Polyclonal Antibody detects endogenous levels of ULK2


Synthetic Peptide of ULK2





Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000






ULK2 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


1 mg/ml


ULK2 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Serine/threonine-protein kinase ULK2 antibody, Unc-51-like kinase 2 antibody

Database links

Human UniProt/Swiss-Prot:Q8IYT8;Mouse UniPort/Swiss-Prot: Q9QY01;Rat UniProt/Swiss-Port: D3Z9J7;Human Entrez Gene: 9706;Mouse Entrez Gene: 29869;Rat Entrez Gene: Rn.17602

Protein names

Serine/threonine-protein kinase ULK2 , Unc-51-like kinase 2

Protein function

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons. / ATP + a protein = ADP + a phosphoprotein.

Protein sequence and domain

The CTD-like region mediates membrane-binding and incorporation into large protein complexes. / Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. / Contains 1 protein kinase domain.

Protein post-translational modifications

Autophosphorylated. In response to nutrient limitation, probably phosphorylated and activated by AMPK, leading to activate autophagy.

Protein cellular localization

Cytoplasmic vesicle membrane / Peripheral membrane protein

Research area

All research areas>Kinases and Phosphatases>ULK2
(View all antibody categories related to Kinases and Phosphatases)


AntibodyPlus can customize ULK2 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.


St John’s Laboratory Ltd.

Product type

Primary antibody


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Antibody customer reviews & validation data - 31

Validation data ID: 31

Submission date: 2016-12-07

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Figure description:

Labeling is very clear

Product name

Anti-Beclin1, Anti-ULK1, Anti-ATG9A, Anti-AMBRA1

Product catalog No.


Product type

Primary antibody


St John's Laboratory Ltd

Application type

Western Blot

Antibody specificity rating


Antibody overall rating


Your comments

I had to wash my membranes for 2 hours after secondary antibody. It takes so much to get rid of impurities.

Detailed protocol

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