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Rabbit Polyclonal ULK2 antibody (STJ98597)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
ULK2 antibody, KIAA0623 antibody,|ATG1B antibody|KIAA0623 antibody|Serine/threonine protein kinase ULK2 antibody|Serine/threonine-protein kinase ULK2 antibody|ULK2 antibody|ULK2_HUMAN antibody|Unc 51 (C. elegans) like kinase 2 antibody|Unc 51 like autophagy activating kinase 2 antibody|Unc 51 like kinase 2 antibody|Unc-51-like kinase 2 antibody|Unc51.2 antibody|Anti-ULK2 antibody (ab97695)
SCBT cat No: To be updated
ULK2 Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
ULK2 Polyclonal Antibody detects endogenous levels of ULK2
Synthetic Peptide of ULK2
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
ULK2 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ULK2 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Serine/threonine-protein kinase ULK2 antibody, Unc-51-like kinase 2 antibody
|Protein names|| |
Serine/threonine-protein kinase ULK2 , Unc-51-like kinase 2
|Protein function|| |
Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons. / ATP + a protein = ADP + a phosphoprotein.
|Protein sequence and domain|| |
The CTD-like region mediates membrane-binding and incorporation into large protein complexes. / Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. / Contains 1 protein kinase domain.
|Protein post-translational modifications|| |
Autophosphorylated. In response to nutrient limitation, probably phosphorylated and activated by AMPK, leading to activate autophagy.
|Protein cellular localization|| |
Cytoplasmic vesicle membrane / Peripheral membrane protein
AntibodyPlus can customize ULK2 Antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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Antibody customer reviews & validation data - 31
Validation data ID: 31
Submission date: 2016-12-07
Labeling is very clear
Anti-Beclin1, Anti-ULK1, Anti-ATG9A, Anti-AMBRA1
Product catalog No.
St John's Laboratory Ltd
Antibody specificity rating
Antibody overall rating
I had to wash my membranes for 2 hours after secondary antibody. It takes so much to get rid of impurities.
There is no extra validation for this product yet.
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