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Rabbit Polyclonal VEGF antibody (STJ97787)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC
Recommended dilution: IHC 1:100-200
Recommended protocols: check protocols
Click or hover above images to see image description for VEGF Rabbit Polyclonal Antibody.
Check alternative names for the antibodyExpand
VEGFA antibody, VEGF antibody,|Folliculostellate cell-derived growth factor antibody|Glioma-derived endothelial cell mitogen antibody|MGC70609 antibody|MVCD1 antibody|Vascular endothelial growth factor A antibody|vascular endothelial growth factor A121 antibody|vascular endothelial growth factor A165 antibody|vascular endothelial growth factor antibody|Vascular permeability factor antibody|VEGF A antibody|Vegf antibody|VEGF-A antibody|VEGF120 antibody|Vegfa antibody|VEGFA_HUMAN antibody|VPF antibody|Anti-VEGFA antibody [VG-1] (ab1316)
SCBT cat No: To be updated
VEGF Rabbit Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
VEGF Rabbit Polyclonal Antibody detects endogenous levels of VEGFA
Recombinant Protein of VEGF
|Recommended dilution|| |
VEGF Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
VEGF Rabbit Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Vascular endothelial growth factor A antibody, VEGF-A antibody, Vascular permeability factor antibody, VPF antibody
|Protein names|| |
Vascular endothelial growth factor A , VEGF-A , Vascular permeability factor , VPF
|Protein function|| |
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
|Protein tissue specificity|| |
Isoform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed. A higher level expression seen in pituitary tumors as compared to the pituitary gland.
|Involvement in disease|| |
Microvascular complications of diabetes 1 (MVCD1) [MIM:603933]: Pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the PDGF/VEGF growth factor family.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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