Rabbit Polyclonal VEGFA antibody (STJ96235)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IF
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal VEGFA antibody (STJ96235)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IHC, ELISA

Recommended dilution: IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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VEGFA antibody, VEGF antibody,|Folliculostellate cell-derived growth factor antibody|Glioma-derived endothelial cell mitogen antibody|MGC70609 antibody|MVCD1 antibody|Vascular endothelial growth factor A antibody|vascular endothelial growth factor A121 antibody|vascular endothelial growth factor A165 antibody|vascular endothelial growth factor antibody|Vascular permeability factor antibody|VEGF A antibody|Vegf antibody|VEGF-A antibody|VEGF120 antibody|Vegfa antibody|VEGFA_HUMAN antibody|VPF antibody|Anti-VEGFA antibody [VG-1] (ab1316)
SCBT cat No: To be updated

Name

VEGF-A Polyclonal Antibody

Catalogue No.

STJ96235

Reactivity

Human, Mouse, Rat

Specificity

VEGF-A Polyclonal Antibody detects endogenous levels of VEGF-A protein.

Immunogen

Synthesized peptide derived from the Internal region of human VEGF-A

Host

Rabbit

Applications

IHC, ELISA

Recommended dilution

IHC 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

27 kDa

Formulation

VEGF-A Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

VEGF-A Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Vascular endothelial growth factor A antibody, VEGF-A antibody, Vascular permeability factor antibody, VPF antibody

Database links

Human UniProt/Swiss-Prot:P15692;Mouse UniPort/Swiss-Prot: Q00731;Rat UniProt/Swiss-Port: B5DEK7;Human Entrez Gene: 7422;Mouse Entrez Gene: 22339;Rat Entrez Gene: Rn.1923

Protein names

Vascular endothelial growth factor A , VEGF-A , Vascular permeability factor , VPF

Protein function

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Protein tissue specificity

Isoform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed. A higher level expression seen in pituitary tumors as compared to the pituitary gland.

Involvement in disease

Microvascular complications of diabetes 1 (MVCD1) [MIM:603933]: Pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the PDGF/VEGF growth factor family.

Protein cellular localization

Secreted

Research area

All research areas>Growth Factors and Hormones>VEGF
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize VEGF-A Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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Immunofluorescence analysis of Mouse kidney tissue

1: VEGF-A Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Mouse spleen tissue

1: VEGF-A Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.


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