No products in the cart.
Rabbit Polyclonal Versican antibody (STJ96239)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC, ELISA
Recommended dilution: IHC 1:100-1:300; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for Versican Polyclonal Antibody.
Check alternative names for the antibodyExpand
VCAN antibody, CSPG2 antibody,|Chondroitin sulfate proteoglycan 2 antibody|Chondroitin sulfate proteoglycan core protein 2 antibody|Chondroitin sulfate proteoglycan core protein, cartilage antibody|CSPG2 antibody|CSPG2_HUMAN antibody|ERVR antibody|GHAP antibody|Glial hyaluronate binding protein antibody|Glial hyaluronate-binding protein antibody|Large fibroblast proteoglycan antibody|PG-M antibody|PGM antibody|VCAN antibody|Versican antibody|Versican core protein antibody|Versican proteoglycan antibody|WGN 1 antibody|WGN antibody|WGN1 antibody|Anti-Versican antibody (ab19345)
SCBT cat No: To be updated
Versican Polyclonal Antibody
|Catalogue No.|| |
Versican Polyclonal Antibody detects endogenous levels of Versican protein.
Synthesized peptide derived from Versican at AA range 510-590
|Recommended dilution|| |
IHC 1:100-1:300; ELISA 1:10000;
|Molecular weight|| |
Versican Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Versican Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Versican core protein antibody, Chondroitin sulfate proteoglycan core protein 2 antibody, Chondroitin sulfate proteoglycan 2 antibody, Glial hyaluronate-binding protein antibody, GHAP antibody, Large fibroblast proteoglycan antibody, PG-M antibody
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/P13611">P13611</a>;Rat UniProt/Swiss-Port: <a href="http://www.uniprot.org/uniprot/Q9ERB4">Q9ERB4</a>;Human Entrez Gene: <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1462">1462</a>;Mouse Entrez Gene: <a href="http://www.ncbi.nlm.nih.gov/gene/13003">13003</a>;Rat Entrez Gene: <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=35666">Rn.35666</a>
|Protein names|| |
Versican core protein , Chondroitin sulfate proteoglycan core protein 2 , Chondroitin sulfate proteoglycan 2 , Glial hyaluronate-binding protein , GHAP , Large fibroblast proteoglycan , PG-M
|Protein function|| |
May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.
|Protein tissue specificity|| |
Cerebral white matter and plasma. Isoform V0 and isoform V1 are expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas. Isoform V2 is restricted to normal brain and gliomas. Isoform V3 is found in all these tissues except medulloblastomas.
|Involvement in disease|| |
Wagner vitreoretinopathy (WGVRP) [MIM:143200]: A rare vitreoretinopathy characterized by an optically empty vitreous cavity with fibrillary condensations and a preretinal avascular membrane. Other optical features include progressive chorioretinal atrophy, perivascular sheating, subcapsular cataract and myopia. . Note: The disease is caused by mutations affecting the gene represented in this entry. The pathological mechanism involves a quantitave imbalance of the normally occurring splice variants (PubMed:22739342). .
|Protein sequence and domain|| |
Belongs to the aggrecan/versican proteoglycan family. / Contains 1 C-type lectin domain. / Contains 2 EGF-like domains. / Contains 1 Ig-like V-type (immunoglobulin-like) domain. / Contains 2 Link domains. / Contains 1 Sushi (CCP/SCR) domain.
|Protein post-translational modifications|| |
Phosphorylated by FAM20C in the extracellular medium.
|Protein cellular localization|| |
Secreted > extracellular space > extracellular matrix
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Neurobiology/">Neurobiology</a>><a href="http://antibodyplus.com/product-tag/versican/">versican</a><br><a href="http://antibodyplus.com/product-tag/Neurobiology/"> (View all antibody categories related to Neurobiology)</a>
AntibodyPlus can customize Versican Antibody according to your requirement, including bulk product size,etc. Please contact <a href="mailto:email@example.com">firstname.lastname@example.org</a>. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
Displaying 1 - 1 of 1
Antibody customer reviews & validation data - 78
Validation data ID: 78
Submission date: 2017-01-20
Versican is present within the cytoplasm of embryonic heart cells. This pattern may be real, as another extracellular matrix factor, Fibronectin, also has strong intracellular accumulation. However, more tests are necessary to determine if the intracellular Vcan signal is real, including staining in Vcan knockdown or knockout organisms, Western blot, and immunostaining at other developmental stages.
GFP marks migrating endocardial cells, DAPI marks nuclei.
Rabbit Polyclonal Versican antibody
Product catalog No.
St John's Laboratory Ltd
Antibody specificity rating
Antibody overall rating
Versican is present within the cytoplasm of embryonic heart cells. This pattern may be real, as another extracellular matrix factor, Fibronectin, also has strong intracellular accumulation. However, more tests are necessary to determine if the intracellular Vcan signal is real.
There is no extra validation for this product yet.
Check other extra validated antibodies below: