Rabbit polyclonal YWHAZ antibody (A7639)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal YWHAZ antibody (A7639)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal YWHAZ antibody.

Alternative names:

Check alternative names for the antibody

Expand

HEL4 antibody, YWHAD antibody, KCIP-1 antibody, HEL-S-3 antibody, 14-3-3-zeta antibody
14 3 3 delta antibody|14 3 3 protein zeta/delta antibody|14 3 3 protein/cytosolic phospholipase A2 antibody|14 3 3 zeta antibody|14-3-3 protein zeta/delta antibody|1433Z_HUMAN antibody|Epididymis luminal protein 4 antibody|Epididymis secretory protein Li 3 antibody|HEL S 3 antibody|HEL4 antibody|KCIP-1 antibody|KCIP1 antibody|MGC111427 antibody|MGC126532 antibody|MGC138156 antibody|Phospholipase A2 antibody|Protein kinase C inhibitor protein 1 antibody|Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, delta polypeptide antibody|Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta antibody|Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody|Tyrosine 3/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody|YWHAD antibody|YWHAZ antibody|Anti-14-3-3 zeta antibody (ab51129)

SCBT cat No: sc-293415|sc-1019|sc-31964|sc-31965|

Name

Rabbit polyclonal YWHAZ antibody

Catalogue No.

A7639

Reactivity

Human

Immunogen

A synthetic peptide of human YWHAZ

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 28kDa/Observed: Refer to figures

Formulation

YWHAZ antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

YWHAZ antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HEL4 antibody, YWHAD antibody, KCIP-1 antibody, HEL-S-3 antibody, 14-3-3-zeta antibody

Database links

Human UniProt/Swiss-Prot:P63104

Protein names

HEL4, YWHAD, KCIP-1, HEL-S-3, 14-3-3-zeta

Protein function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Protein sequence and domain

Belongs to the 14-3-3 family.

Protein post-translational modifications

The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Thr-232; inhibits binding of RAF1. Phosphorylated on Ser-58 by PKA and protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53.

Protein cellular localization

Cytoplasm . Melanosome . Note: Located to stage I to stage IV melanosomes.

Background

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5′ UTR but that encode the same protein have been identified for this gene.

Note

AntibodyPlus can customize YWHAZ antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

Displaying 1 - 1 of 1

Antibody customer reviews & validation data - 29

Validation data ID: 29

Submission date: 2016-12-01

View Details

Result figure:
Result figure

Figure description:

YWHAZ was detected to present in 5 different cell lines that were loaded in pairs. There is a strong band within 28kDa region indicating abundancy of of YWHAZ in these cell lines.

Product name

Rabbit polyclonal YWHAZ antibody

Product catalog No.

A7639

Product type

Primary antibody

Supplier

ABclonal

Application type

Western Blot

Antibody specificity rating

Excellent

Antibody overall rating

Excellent

Your comments

Great antibodies. Surprising clean blot for polyclonal antibodies.

Detailed protocol

View Details

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!