Infectious fungal infection has become a serious threat to human health and plays an important role in bacterial sepsis. High-mobility group protein B1...
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High mobility group protein B1 (HMGB1) is an important late-stage medium of sepsis caused by severe infection and participates in the process of...
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OBJECTIVE: To investigate the expression of high mobility group box-1 (HMGB1) mRNA in liver tissue of rats with sepsis induced by Janus kinase...
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Objective To investigate the expression of HMGB1 / RAGE protein in esophageal squamous cell carcinoma and its effect on the prognosis of esophageal...
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HMGB1 is a broad DNA-binding protein involved in maintaining gene stability, regulating DNA transcription and repair. HMGB1 could bind to PRR receptors such...
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OBJECTIVE: To investigate the effect of shRNA targeting HMGB1 on HMGB1 expression and its relationship with invasion and migration of endometrial carcinoma cells....
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Pandemic pneumonia is a common childhood lower respiratory tract infection, is a common community-acquired pneumonia (community-acquired pneumonia, CAP) one. According to the World...
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Epilepsy is one of the most common chronic diseases of the nervous system. The long-term recurrent epileptic seizures have a high incidence of...
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In this study, lupus nephrits (LN) model MRL / faslpr mice and mouse mesangial cells were used to investigate the effects of high...
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Cerebrovascular disease is a serious threat to human health, is the world’s death, disabling one of the major diseases. Cerebrovascular disease is more...
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The findings suggest that during hypoxia HMGB1 upregulates mitochondrial biogenesis in HCC cancer cells promoting tumor survival and proliferation.
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The study set the hypothesis that HMGB1 (such as flagellin, CpG-ODN and LPS), in combination with bacterial components, promote HIV-1 replication. In addition,...
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This is a study to investigate the efficacy of baicalin in infant rodent models and to further explore its underlying mechanisms. Pulmonary hypertension...
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Metastatic spread is the main cause of cancer-related mortality, the lung is the main part of metastatic seeds. The treatment available for patients...
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HMGB1 participates in organ damage and immune rejection after transplantation and may become a marker for successful organ implantation.
Leave a comment | HMGB1 associated molecular patterns (DAMP) has been shown to be involved in the development of multiple organ IRIs.
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HMGB1 can reduce bleeding induced proinflammatory cytokines and neutrophil aggregation and inhibit bleomycin induced lung injury in mice.
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This provides a new idea for elucidating the pathogenesis of RA and provides a new target for the treatment of RA.
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HMGB1 is thought to be a key late proinflammatory mediator of sepsis.
Leave a comment |High-mobility group box 1 (HMGB1) is a conserved nucleoprotein that plays an important role in maintaining nucleosomal stability, DNA recombination, replication, repair and...
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